VITAL SIGNS

Hi Gang,   I’m fresh off the annual BioCom Partnering & Investor Conference  and wanted to share some key takeaways for those who...

Hi Gang!   It’s GROUNDHOG DAY! Don’t we know it. Despite sunshine and optimism  during JPM, recent conversations indicate many of us are...

Hello from the other siiiiiiiide…   I’m back in athleisure today, and boy does it feel GREAT. Another trip around the JPM sun – actual...

Hi Gang,   May I be the first to wish you Happy Holidays! (Halloween counts, right?) I have been thinking about you and, on the heels of...

Hi Gang, As we round the mid-point of 2024, I’ve missed you guys and felt another Vital Signs coming on! How’s everyone feeling out...

Hi Gang, Well… we made it. It has been a rollercoaster of a year – not a fun time to be a CEO. Public company CEOs have been pummeled –...

Hi Gang, Remember me? Much like COVID, Vital Signs is not actually “over”… I am just selectively striking when you least expect it....

Hi Gang! Life is back!!! It has been so fun to run into you at various events around town! For the first time – maybe ever – people are...

Hi Gang, Following up on the previous Vital Signs, a number of biotech CEOs have spoken out publicly about the overturn of Roe v. Wade,...

Hi Gang, What a trying time to be a CEO. When candidates tell me they have top-chair aspirations, I wonder if they’ve considered the...

Hi Gang, Greetings and jubilance from London! I’m working from our UK office this week and quite enjoying double-decker busses, minding...

Hi Gang, On Friday, we hosted a private CEO:CEO forum to address today’s pressing issues. The conversation hovered around two core...

Hi Gang, Soooo… we’ve rounded the 2-year mark and counting with this thing. And ‘this thing’ is now much more than a virus. It’s anxiety...

Hi Gang, In case you’re missing it… Ironically, it’s a beautiful week in San Francisco… nary a raindrop in sight. The market is serving...

Hi Gang, More than 200 C-suite leaders responded to our Vital Signs survey, delivering a rich data set and interesting (and concerning)...

Hi Gang, Ugh. Things flared up in the Bay Area this week, and businesses are taking it upon themselves to require masks. (RRA just...

Last week, two CEO candidates packed a bag, kissed their dogs goodbye, and boarded airplanes. Both visited a company’s headquarters, met...

Hi Gang, The results of the latest Pulse Check are in! A few headlines: This past year, we’ve been as productive, if not more productive...

Hi Gang, Big news in California: All residents over age 16 can get vaccinated starting April 15 (and everyone over age 50 by April 1)!...

Hi Gang, A funny thing happened last weekend. I went into SF for the long weekend, and every place I stopped, I ran into a familiar face....

Hi Gang, We made it!!! Happy New Year, at last! It was an emotional day for me… probably for many of you, too. I first visited...

Hi Gang, We’re almost there… two weeks to go and, thanks to the tireless heroes in our industry, we have two vaccines approved and many...

Hi Gang, A brief note to say THANK YOU for your friendship this year. The Vital Signs community has been such a source of insight,...

Hi Gang, HOLY SMOKES!!! I was taking a little breather from Vital Signs… started running low on material and even lower on inspiration....

Hi Gang, I love this graph from Auren Hoffman (tech investor, CEO, and generally fascinating character): So true. Except are adults...

Hey Gang, It’s been a little while. In case you missed it, this sums up the past few weeks in the Bay Area: Our hearts are with you guys...

Hi Gang, HOLY SMOKES! It’s been a living hell in Northern California over the past two weeks. An unexpected and bizarre lightning storm...

Hi Gang, Holy. Freaking. Cow. It’s been SO. SO. HOT here in California. How hot is it? It’s so hot that I tried to find funny jokes about...

Hi Gang, It turns out 20 years of your life can fit into a pretty small box. I returned to San Francisco this weekend to visit my...

Hi Gang, How many times a day do you consider data? When attempting to solve problems, we often ask, ‘What does the data tell you?’ This...

Hey Gang, It was a big day around here. I got a haircut! First post-COVID cut of 2020, and it feels a lot like a hot shower after a long...

Hi Gang, Perhaps you’ve heard the quote, “Be patient and tough; someday this pain will be useful to you.” (Or, “Perfer et obdura, dolor...

Hi Gang, Ugggghhh, this school opening/not opening thing is an absolute nightmare. How are parents (especially two working parents)...

Hi Gang, Happy July 4th weekend! Or, as I’ve termed it, the “holiday.” Who’s got plans?! Yeah… no one, really. No fireworks. No...

Hi Gang, I’ve been in discussions with a few VCs on a topic and would love to know what you think. In recent years, we’ve seen tremendous...

Hi Gang, This week, I left virtual life for real life. By that I mean that I left my little spot in the woods to road-trip through the...

Hi Gang, When I was in middle school, we were assigned a project called, Create a Country. We had to sort out everything – location,...

Hi Gang, It’s been a tough week. I hope everyone can take some time to reflect and just… breathe... this weekend. We need it. On the...

Hi Gang, Remember when we released the results of the Vital Signs Pulse Check and found that, more than anything, people are just really,...

Hey Gang, On Monday evening, I posted an article shared by a friend – the headline is, Your Black Colleagues May Look Like They’re Okay —...

Hi Gang, So many of you have reached out to ask how other leaders are broaching conversations in the wake of recent events and amid a...

Hi Gang, What do you say? We are all searching for words. And importantly, searching for actions. Statistically, very few of you are...

Hi Gang, Short weeks are the best – we really need more of them. It’s already Friday, and I have big plans to sit in my yard. Just like...

Hi Gang, Among the many things we evaluate in the recruiting process is executive presence. There are definitions and criteria for this,...

Hey Gang, I spent two hours pouring over a spreadsheet this morning, and it was glorious. The exercise was not creative, interactive,...

Hey Gang, I hope you had an amazing long weekend. Even though we couldn’t travel or host big barbeques, at least we got to rest our eyes....

Hey Gang! Vital Signs is taking a break today to ease into the long weekend. Hopefully, you can do the same. (You’re tired. Rest!) Be...

Hey Gang, Yesterday, we released the results of our Vital Signs Pulse Check and called out some interesting data points. I can’t say I...

Hey Gang, I’m pleased to release the results of our second Vital Signs Pulse Check. Please see below (note there are 4 pages). We first...

Hi Gang, Sometimes, the best response is a simple hug. Even if you haven’t experienced tragic death or frightening illness recently,...